Changes In A Surgical Stress Index In Response To Standardized Pain Stimuli During Propofol-remifentanil Infusion

The surgical stress index (SSI) relies on a sum of the normalized pulse beat interval (PBI) and the pulse wave amplitude (PPGA) time sequence of the photoplethysmography. As a measure of the nociception-anti-nociception stability in response to a standardized pain stimulus, SSI was compared with EEG modifications in state and response entropy (SE and RE), PPGA, and heart fee (HR) during varied targeted pseudo-regular-state concentrations of propofol and remifentanil.

Forty ASA I patients have been allotted to one of the four teams to receive a remifentanil step-up/-down effect-compartment goal-managed infusion (Ceremi) of 0, 2, 6, 2, 0 ng ml−1, セクシーコスプレ or 6, 2, 0, 2, 6 ng ml−1, and an effect-compartment goal-controlled propofol infusion (Ceprop) to maintain the SE between 30 and 50 or 15 and 30, respectively. At each steady-state Ceremi, 1688 english maximum change in SSI, SE, RE, PPGA, and HR after a noxious stimulus was compared with the baseline value.

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